Thermo Fisher Scientific Human IL-27 Recombinant Protein, PeproTech
인간 유래 IL-27 재조합 단백질로 HEK293 세포에서 발현됨. 면역 반응 조절 및 T세포 분화 연구에 적합. SDS-PAGE 및 HPLC 기준 90% 이상 순도. TF-1 세포 증식 활성 검증 완료. 연구용으로만 사용 가능.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
Functional Assay (Functional)
- Assay-dependent
In vitro Assay (IV)
- Refer to publications (13 available)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Human, Mouse |
| Expression System | HEK293 cells |
| Amino Acid Sequence | p28 subunit: FPRPPGRPQL SLQELRREFT VSLHLARKLL SEVRGQAHRF AESHLPGVNL YLLPLGEQLP DVSLTFQAWR RLSDPERLCF ISTTLQPFHA LLGGLGTQGR WTNMERMQLW AMRLDLRDLQ RHLRFQVLAA GFNLPEEEEE EEEEEEEERK GLLPGALGSA LQGPAQVSWP QLLSTYRLLH SLELVLSRAV RELLLLSKAG HSVWPLGFPT LSPQP EBI3 subunit: RKGPPAALTL PRVQCRASRY PIAVDCSWTL PPAPNSTSPV SFIATYRLGM AARGHSWPCL QQTPTSTSCT ITDVQLFSMA PYVLNVTAVH PWGSSSSFVP FITEHIIKPD PPEGVRLSPL AERQLQVQWE PPGSWPFPEI FSLKYWIRYK RQGAARFHRV GPIEATSFIL RAVRPRARYY VQVAAQDLTD YGELSDWSLP ATATMSLGK |
| Molecular Weight | 47.8 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 90% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | <1 EU/µg |
| Activity | Stimulates proliferation of human TF-1 cells (ED50: 400–500 ng/ml) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human IL-27 produced from HEK293 cells is a non-disulfide-linked, heterodimeric protein composed of a 209 amino acid EBI3 subunit and a 215 amino acid IL-27-p28 subunit, totaling 424 amino acid residues.
The calculated molecular weight of the associated IL-27 subunits is 47.8 kDa.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
IL-27 (Interleukin 27) is a cytokine belonging to the IL-12 family, composed of EBI3 and p28 subunits. It is produced by activated dendritic cells and macrophages in response to Toll-like receptor ligands and pro-inflammatory cytokines.
IL-27 promotes CD4+ T cell differentiation to the Th1 lineage by inducing T-bet expression and upregulating IL-12Rβ2, thereby suppressing Th2 and Th17 differentiation.
It acts via WSX-1 and gp130 receptors, activating the Jak/STAT signaling cascade involved in immune regulation.
IL-27 may have therapeutic potential against cancer through CD8+ T-cell mediated anti-tumor activity.
In humans, the IL-27 gene is located on the p arm of chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Human IL-35 Recombinant Protein, PeproTech
1,669,600원
Thermo Fisher Scientific
Thermo Fisher Scientific Human IL-36 gamma (IL-1F9) Recombinant Protein, PeproTech
139,800원
Thermo Fisher Scientific
Thermo Fisher Scientific Human IL-27 Recombinant Protein, PeproTech
138,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Human IL-36 beta (IL-1F8) Recombinant Protein, PeproTech
139,800원
Thermo Fisher Scientific
Thermo Fisher Scientific Human IL-36 alpha (IL-1F6) Recombinant Protein, PeproTech
139,800원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|