Thermo Fisher Scientific Ku80 Monoclonal Antibody (111)
Ku80 단백질을 표적하는 mouse monoclonal antibody로 Western blot, IHC, ICC/IF, Flow cytometry, IP 등 다양한 응용에 사용 가능. Human, Mouse, Non-human primate 시료에 반응하며, 4°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.4 - 1 µg/mL | View 29 publications |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:20 - 1:200 | View 11 publications |
| Flow Cytometry (Flow) | 0.5 µg/test | View 1 publication |
| Immunoprecipitation (IP) | 2 µg/mL | View 7 publications |
| Neutralization (Neu) | - | View 1 publication |
| Gel Shift (GS) | - | View 4 publications |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Fruit fly, Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 111 |
| Immunogen | Human B cell nuclei from plasmacytoid 2p68 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10983840 |
Product Specific Information
MA5-12933 targets Ku (p80) in FACS, ICC/IF, IP, and WB applications and shows reactivity with Human, Mouse, and Non-human primate samples.
This antibody does not cross-react with mouse in immunofluorescent applications but does react with mouse in FACS applications.
The immunogen is human B cell nuclei from plasmacytoid 2p68 cells.
Target Information
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5.
Ku is the DNA-binding component of the DNA-dependent protein kinase and functions with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand breaks by non-homologous end joining and in V(D)J recombination events.
A rare microsatellite polymorphism in this gene is associated with cancer in patients with varying radiosensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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