Thermo Fisher Scientific CD6 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal CD6 항체. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관하며, 4°C 단기 또는 -20°C 장기 보관 가능. 연구용 전용 제품.
- 카탈로그번호
- PA586923
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD6 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 250–300 of Human CD6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803681 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia (ALL) cells.
CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse.
CD6–ALCAM mediated cell adhesion is important for T cell proliferation.
CD6 may exert some of its functions via association with CD5, possibly fine-tuning CD5 signaling.
Ligation of CD6 has an anti-apoptotic role in chronic lymphocytic leukemia B cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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