Thermo Fisher Scientific Human ACE2 (IN1) Synthetic Peptide
인간 ACE2 단백질의 중심부 17개 아미노산 서열로 구성된 합성 펩타이드. 항체 PA5-20039의 블로킹 펩타이드로 사용 가능. 혈관 및 심장 생리 연구용. 액상 형태, 200 µg/mL, -20°C 보관.
- 카탈로그번호
- PEP0158
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the center of human ACE2.
PEP-0158 can be used as a blocking peptide with polyclonal antibody PA5-20039.
Target Information
Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology.
In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis.
ACE2 has also been shown to be a functional receptor of the SARS coronavirus.
Its normal function is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII.
Lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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