Thermo Fisher Scientific RALBP1 Monoclonal Antibody (OTI2A6), TrueMAB
RALBP1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC, ICC, IP 등 다양한 응용에 적합합니다. HEK293T 세포에서 발현된 전장 인간 RALBP1 단백질을 면역원으로 제작되었습니다. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 4 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A6 |
| Immunogen | Full length human recombinant protein of human RALBP1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
RALBP1 specifically activates hydrolysis of GTP bound to RAC1 and CDC42, but not RALA.
It mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX), serving as a major ATP-dependent transporter of glutathione conjugates and DOX in erythrocytes.
RALBP1 functions as a scaffold protein forming endocytotic complexes during interphase and interacts with CDC2 to regulate endocytosis. One of its substrates is EPN1/Epsin.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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