Thermo Fisher Scientific ZUFSP Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:100

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthesized peptide derived from human ZUFSP.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.8 mg/mL

Purification

affinity chromatography

Storage buffer

PBS, pH 7.4, with 40% glycerol

Contains

0.05% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2692080

Product Specific Information

Specficity: The antibody detects endogenous levels of total ZUFSP protein.

Target Information

Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves Lys-63-linked long polyubiquitin chains. Shows only weak activity against Lys-11 and Lys-48-linked chains. Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage. Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.