Thermo Fisher Scientific SALL1 Polyclonal Antibody
인간, 마우스, 랫트에서 반응하는 Rabbit Polyclonal 항체로 SALL1 단백질 검출용. Western blot 및 Immunocytochemistry에 적합. Affinity chromatography로 정제된 액상 형태, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SALL1 (Accession Q9NSC2), corresponding to amino acid residues R4–E54 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900498 |
Product Specific Information
Antibody detects endogenous levels of total SALL1.
Target Information
Sall1 encodes a zinc finger protein that functions as a transcriptional repressor and interacts with histone deacetylase and components of the chromatin remodeling NuRD complex. It acts as a microglial signature gene and is expressed abundantly in mesenchyme-derived structures, renal tubules, and podocytes. Sall1 is essential for maintaining nephron progenitor cell stemness by preventing premature differentiation. Mutations in SALL1 cause Townes-Brocks syndrome and bronchio-oto-renal syndrome, leading to developmental anomalies such as dysplastic ears, polydactyly, and imperforate anus. Two transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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