Thermo Fisher Scientific Cadherin-6 (CDH6)/K-Cadherin Monoclonal Antibody (CDH6/3191)
인체 Cadherin-6 단백질을 인식하는 마우스 단클론 항체. IHC(P), IHC(PFA), Peptide Array 등 다양한 응용에 적합. 단백질 A/G로 정제된 액상 항체로, 4°C 보관. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CDH6/3191 |
| Immunogen | Recombinant fragment (around aa 250–450) of human Cadherin 6 protein (CDH6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cadherins are a family of transmembrane glycoproteins involved in Ca²⁺-dependent cell-cell interactions and play essential roles in tissue integrity and morphogenesis.
They are classified into type I and type II subgroups:
- Type I: E-cadherin (cadherin-1), N-cadherin (cadherin-2), P-cadherin (cadherin-3), R-cadherin (cadherin-4)
- Type II: K-cadherin (cadherin-6), OB-cadherin (cadherin-11)
Cadherin-6 is expressed in the proximal tubule epithelium of the kidney, from which most renal cell carcinomas are derived.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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