Thermo Fisher Scientific alpha-1b Adrenergic Receptor Polyclonal Antibody

Applications

Western Blot (WB)

• Tested dilution: 1:500–1:3,000
• Recommended positive control: Mouse brain

Product Specifications

Product Specific Information

• Recommended positive controls: Mouse brain
• Predicted reactivity: Mouse (100%), Rat (100%), Dog (100%), Rabbit (100%), Bovine (100%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The alpha-1b adrenoceptor is an adrenergic receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor expression is associated with benign prostatic hyperplasia (BPH).
This receptor also acts as a proto-oncogene when constitutively activated, inducing neoplastic transformation in transfected cell lines.
It is expressed in adrenal, aorta, blood, brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.