Thermo Fisher Scientific alpha-1b Adrenergic Receptor Polyclonal Antibody
Rabbit polyclonal antibody targeting alpha-1b Adrenergic Receptor. Validated for Western blot with 1:500–1:3,000 dilution. Detects multiple species including mouse, rat, dog, rabbit, and bovine. Supplied as liquid, 1 mg/mL, stored at 4°C short term or ...
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Applications
Western Blot (WB)
- Tested dilution: 1:500–1:3,000
- Recommended positive control: Mouse brain
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 347–440 of alpha-1b Adrenergic Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2544596 |
Product Specific Information
- Recommended positive controls: Mouse brain
- Predicted reactivity: Mouse (100%), Rat (100%), Dog (100%), Rabbit (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The alpha-1b adrenoceptor is an adrenergic receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor expression is associated with benign prostatic hyperplasia (BPH).
This receptor also acts as a proto-oncogene when constitutively activated, inducing neoplastic transformation in transfected cell lines.
It is expressed in adrenal, aorta, blood, brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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