Thermo Fisher Scientific CRHR1 Polyclonal Antibody
Thermo Fisher Scientific의 CRHR1 Polyclonal Antibody는 Western blot과 IHC(P) 분석에 적합한 Rabbit IgG 항체입니다. 인간 CRFR1의 53–147 아미노산 영역을 기반으로 제작되었으며, 마우스, 랫, 토끼 등에서 높은 반응성을 보입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | — |
Product Specifications
| Category | Description |
|---|---|
| Published species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 53–147 of Human CRFR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2544597 |
Product Specific Information
- Recommended positive control: Mouse brain
- Predicted reactivity: Mouse (100%), Rat (100%), Rabbit (100%), Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors.
Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease.
Multiple isoforms of CRFR1 are produced by alternative splicing.
CRFR1 has been reported to be expressed in the pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin.
ESTs have been isolated from human brain, eye, colon, and embryo libraries.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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