Thermo Fisher Scientific Tensin 3 Polyclonal Antibody
Tensin 3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인체 유래 항원으로 제작되었으며, 1 mg/mL 농도의 액상 형태입니다. 세포 구조 유지 및 신호전달 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TNS3 (Accession Q68CZ2), corresponding to amino acid residues L1055–S1105. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900656 |
Product Specific Information
Antibody detects endogenous levels of total TENS3.
Target Information
The Tensin (Tns) family of proteins is involved in the maintenance of cellular structure by anchoring actin filaments at the focal adhesion via F-actin binding and capping activities.
Tns proteins also contain a Src homology 2 (SH2) domain and can be phosphorylated, suggesting a role in signal transduction cascades.
These characteristics indicate that Tns proteins may link the cytoskeleton and signal transduction pathways.
Tns3 (also known as TEM6 or TENS1) localizes to the focal adhesions of the plasma membrane. It is predominantly expressed in thyroid and placenta but also found in heart, liver, brain, prostate, pancreas, kidney, lung, skeletal muscle, and white blood cells.
Tns3 is essential for proper growth and development, as suggested by growth retardation and death in Tns3 knockout mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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