Thermo Fisher Scientific RAR gamma-1 Polyclonal Antibody
RAR gamma-1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 최적화되어 있으며 인간 및 마우스에 반응. 합성 펩타이드 면역원 사용, 친화 크로마토그래피 정제. 장기 보관 시 -20°C에서 냉동 보관 권장.
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Applications
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human RARG (aa 20–69) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2884108 |
Product Specific Information
- Immunogen sequence:
YPGAGFPFAF PGALRGSPPF EMLSPSFRGL GQPDLPKEMA SLSVETQSTS - Storage guidance:
For short term use, store at 2–8°C up to 1 week.
For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. - Predicted homology:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Sheep: 100%
Target Information
Retinoic acid, a metabolite of vitamin A, is essential for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. It functions via the nuclear protein retinoic acid receptor (RAR), part of the steroid and thyroid hormone receptor superfamily that regulates gene expression by binding specific DNA response elements.
RAR has three subtypes: alpha, beta, and gamma. Two main isoforms of RAR gamma exist:
- RAR gamma-1: predominantly expressed in skin
- RAR gamma-2: expressed early in embryogenesis and embryonal carcinoma cells
RAR gamma is also known as RARD, and the corresponding gene for RAR gamma-1 is NR1B3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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