Thermo Fisher Scientific CD200 Polyclonal Antibody
CD200 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 적합합니다. 인간, 생쥐, 랫트 반응성을 가지며 항원 친화 크로마토그래피로 정제되었습니다. 동결건조 형태로 제공되며, 재구성 시 500 µg/mL 농도로 사용 가능합니다.
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Applications
- Western Blot (WB): 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human CD200/OX2 recombinant protein (Position: Q31–K231) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2746083 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains and belongs to the immunoglobulin superfamily. It is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation.
Homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies in mouse and rat suggest that CD200 may regulate myeloid cell activity and deliver an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants encoding different isoforms of CD200 have been found.
Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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