Thermo Fisher Scientific CLIP1 Polyclonal Antibody
CLIP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 고품질 항체로 안정적 액상 형태 제공.
- 카탈로그번호
- PA530946
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–200 of Human CLIP-170 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548420 |
Product Specific Information
- Recommended positive controls: 293T, A431, Raji
- Predicted reactivity: Mouse (88%), Bovine (89%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CLIP170 was initially identified as a new type of intermediate filament-associated protein highly expressed in Reed-Sternberg cells, diagnostic for Hodgkin’s disease. It localizes at microtubule plus ends and is required for endocytic carrier vesicle binding. CLIP170 interacts with LIS1 to regulate dynein/dynactin binding to microtubules and is involved in lamellipodia formation and cell invasion by regulating the release of kinesin and IQGAP1 from a protein complex containing CLIP170 and Rac1. At least two isoforms of CLIP170 are known.
⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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