Thermo Fisher Scientific CCDC79 Polyclonal Antibody
인간 CCDC79 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC 및 ELISA에 사용 가능. Protein G 정제, 3 mg/mL 농도, PBS/glycerol buffer에 보관. -20°C 이하에서 보관하며 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:200
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Telomere repeats-binding bouquet formation protein 1 (301–550 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C (if preferred) |
| Shipping Conditions | Wet ice |
| RRID | AB_3091563 |
Target Information
Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nuclear inner membrane, a crucial step for homologous pairing and synapsis.
Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes.
In early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA.
TERB1 mediates association with the shelterin/telosome complex via interaction with TERF1, promoting telomeric DNA attachment.
Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex. Also recruits cohesin to telomeres to develop structural rigidity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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