Thermo Fisher Scientific Claudin 5 Monoclonal Antibody (4C3C2)
Claudin-5 단백질을 인식하는 Mouse monoclonal antibody(클론 4C3C2). Western blot, IHC, ICC 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A로 정제된 0.5 mg/mL 액상 형태로 제공되며, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 112 publications |
| Immunohistochemistry (IHC) | - | View 75 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20 | View 7 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 10 publications |
| Immunocytochemistry (ICC/IF) | - | View 59 publications |
| Flow Cytometry (Flow) | - | View 2 publications |
| ELISA | Assay-dependent | View 2 publications |
| Immunoprecipitation (IP) | - | View 1 publication |
| in situ PLA (PLA) | - | View 1 publication |
| In vitro Assay (IV) | - | View 1 publication |
| Miscellaneous PubMed (Misc) | - | View 13 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Amphibian, Bovine, Chicken, Cynomolgus monkey, Dog, Guinea pig, Human, Mouse, Pig, Rat, Sheep, Xenopus, Zebrafish |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C3C2 |
| Immunogen | Synthetic peptide derived from the mouse Claudin-5 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533200 |
Additional Formats:
Target Information
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands act as physical barriers to prevent solutes and water from passing through the paracellular space between epithelial or endothelial cell sheets. They also play critical roles in maintaining cell polarity and signal transduction. Differential expression of this gene has been observed in various malignancies including breast, ovarian, liver, urinary, prostate, lung, head and neck, and thyroid cancers. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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