Thermo Fisher Scientific Claudin 5 Monoclonal Antibody (4C3C2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 112 publications 112 publications

Immunohistochemistry (IHC)

-

View 75 publications 75 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20

View 7 publications 7 publications

Immunohistochemistry (Frozen) (IHC (F))

-

View 10 publications 10 publications

Immunocytochemistry (ICC/IF)

-

View 59 publications 59 publications

Flow Cytometry (Flow)

-

View 2 publications 2 publications

ELISA (ELISA)

Assay-dependent

View 2 publications 2 publications

Immunoprecipitation (IP)

-

View 1 publication 1 publication

in situ PLA (PLA)

-

View 1 publication 1 publication

In vitro Assay (IV)

-

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

-

View 13 publications 13 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Amphibian, Bovine, Chicken, Cynomolgus monkey, Dog, Guinea pig, Human, Mouse, Pig, Rat, Sheep, Xenopus, Zebrafish

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

4C3C2

Immunogen

Synthetic peptide derived from the mouse Claudin-5 protein

Conjugate

Unconjugated Unconjugated Unconjugated

View additional formats

• Alexa Fluor 488
• Request custom conjugation

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.1% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533200

Target Information

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.