Thermo Fisher Scientific Calpain 5 Polyclonal Antibody
Calpain 5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, ICC/IF, ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도 Affinity Chromatography 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 361–640 of human CAPN5 (NP_004046.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914670 |
Product Specific Information
- Positive test controls: SKOV3, Mouse thymus, Mouse brain, Mouse spinal cord
- Immunogen sequence:
GAWTLHEDPR QNRGGGCINH KDTFFQNPQY IFEVKKPEDE VLICIQQRPK RSTRREGKGE NLAIGFDIYK VEENRQYRMH SLQHKAASSI YINSRSVFLR TDQPEGRYVI IPTTFEPGHT GEFLLRVFTD VPSNCRELRL DEPPHTCWSS LCGYPQLVTQ VHVLGAAGLK DSPTGANSYV IIKCEGDKVR SAVQKGTSTP EYNVKGIFYR KKLSQPITVQ VWNHRVLKDE FLGQVHLKAD PDNLQALHTL HLRDRNSRQP SNLPGTVAVH ILSSTSLMAV
Target Information
Calpains are calcium-dependent cysteine proteases involved in signal transduction across various cellular processes. A functional calpain protein consists of an invariant small subunit and one of a family of large subunits. CAPN5 is one of the large subunits. Unlike some calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Due to its similarity to the Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also referred to as HTRA3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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