Thermo Fisher Scientific Fibulin 1 Polyclonal Antibody
Fibulin-1 단백질을 검출하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간·생쥐·랫트 반응성. Western blot에 적합하며 고순도(>95%) 항원 친화 정제 제품. 장기 보관 시 -20°C에서 안정적으로 유지.
- 카탈로그번호
- PA537163
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Fibulin 1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in human Fibulin-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553938 |
Product Specific Information
This antibody detects endogenous Fibulin-1 protein at a molecular weight of approximately 77 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Fibulin-1 is a modular glycoprotein component of the elastic extracellular matrix fibers, basement membranes, and blood.
It self-associates and binds to calcium, fibronectin, laminin, nidogen, and fibrinogen.
These interactions may explain its association with basement membranes, connective tissue, elastic fibers, and fibrin clots.
Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and may act as both a metastasis agent and a predictive marker for cancer aggressiveness.
Other studies suggest Fibulin-1 inhibits cancer cell motility with increasing exposure.
The exact cellular function of Fibulin-1 remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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