Thermo Fisher Scientific Mu-Calpain Polyclonal Antibody
Mu-Calpain 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF, Flow Cytometry 등에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용.
- 카탈로그번호
- PA587342
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human Calpain 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2804082 |
Product Specific Information
Purity is greater than 95% by SDS-PAGE.
Target Information
Calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that function as nonlysosomal, intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers composed of distinct large catalytic subunits and a common small regulatory subunit.
The CAPN1 gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been identified.
Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive, and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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