Thermo Fisher Scientific Phospho-Lamin A/C (Ser22) Polyclonal Antibody
인간, 생쥐, 랫트에 반응하는 Rabbit Polyclonal 항체로 Lamin A/C Ser22 인산화 부위를 검출. IHC, ICC, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 안정적인 PBS/glycerol 저장용액 구성.
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Thermo Fisher Scientific Phospho-Lamin A/C (Ser22) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human Lamin A/C around the phosphorylation site of Ser22 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Lamins are intermediate filament proteins forming a matrix on the inner surface of the nuclear envelope. They exist in three forms (A, B, and C) and are expressed in various cell types. Lamins A and C are alternatively spliced products of the LMNA gene, which is associated with several disorders such as:
- Emery-Dreifuss muscular dystrophy
- Dunnigan-type familial partial lipodystrophy (FPLD)
- Limb-girdle muscular dystrophy (LGMD1B)
- Dilated cardiomyopathy (CMD1A)
- Axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1)
- Mandibuloacral dysplasia (MAD)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: BS-3254R_Lamin_AC_P02545-1_Rabbit.svg, BS-3254R_Lamin_AC_P02545-1_Rabbit_PDP.jpeg)
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