Thermo Fisher Scientific GATA-3 (Breast and Urothelial Marker) Monoclonal Antibody (GATA3/2688)
GATA-3 단백질을 표적하는 단클론 항체로, 유방 및 요로상피 마커 연구에 적합합니다. Western blot, Flow cytometry, ELISA 등 다양한 응용에 사용 가능하며, 인간 시료 반응성. 단백질 A/G 정제, 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 1–2 µg/10^6 cells
ELISA
- Tested Dilution: Assay-dependent
Peptide Array
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GATA3/2688 |
| Immunogen | Recombinant fragment of human GATA3 protein (around aa 357–436) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The genes for all four subunits of the T-cell antigen receptor (alpha, beta, gamma, and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all four TCR genes. GATA3 is an enhancer-binding protein containing a zinc finger domain, expressed abundantly in T-lymphocyte lineage, and participates in T-cell receptor gene activation through enhancer binding. Labastie et al. (1994) cloned the human gene and the 5′ end of the mouse gene. The human gene comprises six exons distributed over 17 kb of DNA, with two zinc fingers encoded by separate exons conserved with GATA1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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