Thermo Fisher Scientific PYDC1 Monoclonal Antibody (OTI5D12), TrueMAB
인간 PYDC1 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. 동결건조 형태로 제공되며, PBS 완충액과 8% 트레할로스를 포함합니다. 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D12 |
| Immunogen | Full length human recombinant protein of PYDC1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ASC2 associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-κB and pro-caspase-1 activation.
It suppresses the kinase activity of the NF-κB inhibitor kinase (IKK) complex, reduces expression of NF-κB–inducible genes, and inhibits NF-κB activation by cytokines and LPS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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