Thermo Fisher Scientific SMARCAL1 Polyclonal Antibody
Human SMARCAL1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PA554181
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SMARCAL1 (Recombinant protein control fragment, Product # RP-91637) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647610 |
Product Specific Information
Immunogen sequence:
SYELGQGHAQ ASPEIRFTPF ANPTHKPLAK PKSSQETPAH SSGQPPRDAK LEAKTAKASP SGQNISYIHS SSESVTPRTE GRLQQKSGSS VQKGVNSQKG KCVRNGDRFQ VLIGYNAELI AVFKTLPSKN YDPDTKTWNF S
Highest antigen sequence identity to the following orthologs:
- Mouse: 40%
- Rat: 39%
Target Information
PRKCQ is a calcium-independent, novel isoform that is important in transducing signals in T lymphocytes. Interaction of a T lymphocyte with an antigen-presenting cell results in clustering of the T cell antigen receptor (TCR) and the recruitment of a large signaling complex to the site of cell-cell contact. PRKCQ is essential for TCR-mediated activation. PKC theta plays a role in pathways that link the TCR signaling complex to the activation of NF-kappa B in mature T lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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