Thermo Fisher Scientific Complement C5a Polyclonal Antibody
Thermo Fisher Scientific의 Complement C5a Polyclonal Antibody는 마우스 및 랫트 시료에 반응하는 Rabbit IgG 항체입니다. Western blot과 IHC(P) 분석에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 동결 건조 형태로 제공되며, 재구성 후 500 µg/mL 농도로 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a sequence at the N-terminus of rat C5a (1–18aa, DLQLLHQKVEEQAAKYKH) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746007 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell-killing processes. It consists of alpha and beta polypeptide chains linked by a disulfide bridge. The activation peptide C5a, an anaphylatoxin with spasmogenic and chemotactic activity, is derived from the alpha chain via cleavage with a convertase. The C5b cleavage product forms a complex with complement component C6, initiating formation of the membrane attack complex. Mutations in this gene cause complement component 5 deficiency, leading to recurrent infections, and are associated with susceptibility to liver fibrosis and rheumatoid arthritis.
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For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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