
Thermo Fisher Scientific ALDH3A2 Monoclonal Antibody (OTI2A7), TrueMAB
인간 ALDH3A2 단백질을 인식하는 마우스 단클론 항체로, WB, IHC, Flow Cytometry에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다. 고순도 친화 크로마토그래피 정제 제품입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A7 |
| Immunogen | Full length human recombinant protein of human ALDH3A2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze oxidation of various aldehydes. These enzymes play a major role in detoxifying aldehydes generated by alcohol metabolism and lipid peroxidation.
Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjögren-Larsson syndrome, characterized by ichthyosis, mental retardation, and spastic diplegia. The pathogenesis is linked to abnormal lipid accumulation, aldehyde Schiff base formation, or defective eicosanoid metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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