Thermo Fisher Scientific Cdc42EP5 Polyclonal Antibody
Rabbit polyclonal antibody against human Cdc42EP5 for Western blot applications. Recognizes N-terminal region peptide of BORG3. Supplied as liquid, 1 mg/mL concentration. For research use only; store at -20°C.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the N-terminal region of human BORG3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2555677 |
Target Information
Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. It may also play a role in septin organization and in inducing pseudopodia formation in fibroblasts.
[Provided by RefSeq, Jul 2013]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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