Thermo Fisher Scientific LAMTOR3 Polyclonal Antibody
LAMTOR3 단백질을 인식하는 Thermo Fisher의 토끼 폴리클로날 항체로, WB 및 ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제. PBS/글리세롤 버퍼에 보관하며 -20°C에서 안정적.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LAMTOR3 (Accession Q9UHA4), corresponding to amino acid residues A36–L86 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899394 |
Product Specific Information
This antibody detects endogenous levels of total LAMTOR3.
Target Information
The LAMTOR3 gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein localizes to late endosomes via the mitogen-activated protein-binding protein-interacting protein and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2.
Studies in mouse orthologs indicate roles in regulating late endosomal traffic and cell proliferation. Multiple alternatively spliced transcript variants have been observed, and a pseudogene is located on chromosome 13q.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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