Thermo Fisher Scientific Estrogen Receptor, alpha (Marker of Estrogen Dependence) Monoclonal Antibody (ESR1/3373)
인간 Estrogen Receptor alpha(ESR1)를 인식하는 단클론 항체로, IHC(P), IHC(PFA), Peptide Array 등 다양한 응용에 적합합니다. 단백질 A/G로 정제된 액상 형태이며, 4°C 보관. 연구용으로만 사용됩니다.
- 카탈로그번호
- 2099-MSM23-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Estrogen Receptor, alpha (Marker of Estrogen Dependence) Monoclonal Antibody (ESR1/3373)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ESR1/3373 |
| Immunogen | Recombinant full-length human Estrogen Receptor alpha protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor that, upon binding to estrogen, undergoes a conformational change enabling dimerization and binding to estrogen response elements (ERE) in DNA. This binding regulates gene transcription through coactivator or corepressor recruitment.
Two forms exist: ER alpha (ESR1) and ER beta (ESR2), encoded by separate genes. Alternative RNA splicing produces at least four ER-alpha isoforms (66 kDa, 53 kDa, 47 kDa, 35 kDa). Estrogen receptors are broadly expressed and are critical for sexual development, reproductive function, and bone physiology. They are implicated in diseases such as breast cancer, endometrial cancer, and osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 제품 관련 이미지가 있을 경우 이 섹션에 배치합니다)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.