Thermo Fisher Scientific IRF4 Polyclonal Antibody
IRF4 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 및 설치류 등 다양한 종에 반응합니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 보존제가 포함되지 않습니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues around Pro173 of human IRF4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10984954 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other family members at physiological levels.
Target Information
The IRF (interferon regulatory factor) family of transcription factors are characterized by a unique tryptophan pentad repeat DNA-binding domain. The IRFs regulate interferons in response to viral infection and control interferon-inducible genes.
IRF4 is lymphocyte-specific and negatively regulates toll-like receptor (TLR) signaling, central to innate and adaptive immune activation.
A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be associated with multiple myeloma. Alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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