Thermo Fisher Scientific GADD45A Monoclonal Antibody (OTI2B7), TrueMAB
인간 GADD45A 단백질을 인식하는 마우스 모노클로날 항체. Western blot에 최적화되어 있으며 1:4,000 희석에서 검증됨. Affinity chromatography로 정제된 액상 항체로, PBS/BSA/glycerol buffer에 보관. 세포 스트레스 반응 연구용.
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Applications
- Western Blot (WB): Tested dilution 1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B7 |
| Immunogen | Full length human recombinant protein of human GADD45A produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
GADD45 alpha, beta, and gamma are an evolutionarily conserved family of nuclear proteins functioning as stress sensors for physiological and environmental damage.
They are required for activation of the G2/M checkpoint induced by UV radiation or alkylating agents.
GADD45-induced G2/M checkpoint is regulated through inactivation of Cdc2-cyclin B1 kinase.
GADD45 forms a complex with p21 and Cdc2, serving as a core for interaction with other cell cycle regulators.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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