
ELK Biotechnology RN103 rabbit pAb
RN103 rabbit pAb는 인간 RN103 단백질을 인식하는 고품질 폴리클로날 항체로, WB 및 IHC 실험에 적합합니다. 엔도플라스믹 레티큘럼 막 단백질을 타겟으로 하며, 우수한 특이성과 재현성을 제공합니다. 장기 보관 가능(-20°C, 1년).
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ELK Biotechnology RN103 rabbit pAb
제품 개요
RN103 rabbit pAb는 인간 RN103 단백질을 인식하는 폴리클로날 항체로, Western blot(WB) 및 Immunohistochemistry(IHC)에 사용됩니다. 이 항체는 높은 특이성과 안정성을 제공하며, 엔도플라스믹 레티큘럼 막 단백질 검출에 적합합니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Product name | RN103 rabbit pAb |
| Applications | WB; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300 |
| Immunogen | Synthesized peptide derived from human RN103 (AA range: 243–293) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 7844 |
| Human Swiss-Prot No | O00237 |
| Cellular localization | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by electroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants.
The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene. [provided by RefSeq, Oct 2011]
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