
ELK Biotechnology SMCA5 rabbit pAb
SMCA5 단백질을 인식하는 토끼 폴리클로날 항체로, WB 실험에 적합합니다. 인간 및 생쥐 시료에 반응하며, 핵 및 염색체에 위치하는 단백질 검출에 활용됩니다. -20°C에서 1년 보관 가능하며, 고순도 IgG 형태로 제공됩니다.
- 카탈로그번호
- ES13053-xxxxx (2개 옵션)
- 판매단위
- pk
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제품명
SMCA5 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human SMCA5 (AA range: 851–901) |
| Species Reactivity | Human; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 8467 |
| Human Swiss-Prot No | O60264 |
| Storage | -20°C / 1 year |
| Host | Rabbit |
세포 내 위치
Nucleus, Chromosome. Localizes to mitotic chromosomes (PubMed:12972596).
Co-localizes with RSF1 in the nucleus (PubMed:12972596).
Co-localizes with PCNA at replication foci during S phase (PubMed:15543136).
Co-localizes with BAZ1B/WSTF at replication foci during late-S phase (PubMed:15543136).
Recruited to DNA damage sites following interaction with SIRT6 (PubMed:23911928).
배경 정보
The protein encoded by this gene is a member of the SWI/SNF family of proteins.
Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes.
The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II.
The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. [provided by RefSeq, Jul 2008]
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