Thermo Fisher Scientific GM-CSF Monoclonal Antibody (404CE 10A8), Biotin
인간 GM-CSF에 특이적인 단클론성 항체로 ELISA 검출용으로 적합. Biotin으로 표지되어 있으며 Protein A로 정제됨. 0.5 mg/mL 농도의 액상 형태로 제공되며 4°C에서 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific GM-CSF Monoclonal Antibody (404CE 10A8), Biotin
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 404CE 10A8 |
| Immunogen | Purified recombinant human GM-CSF |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 5 mg/mL BSA |
| Contains | 0.5 mg/mL sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536271 |
Product Specific Information
This antibody can be used as a detection antibody in ELISA applications.
Target Information
The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at chromosome region 5q31, associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene promotes tissue inflammation, and elevated cytokine levels, including GM-CSF, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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