Thermo Fisher Scientific P2Y1 Monoclonal Antibody (4G5B7)
인간 P2Y1 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, WB, IHC, Flow Cytometry, ELISA 등 다양한 응용에 사용 가능. 고순도 Protein G 정제, 1 mg/mL 농도, PBS 버퍼 및 sodium azide 함유. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Flow Cytometry (Flow) | 1:200–1:400 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G5B7 |
| Immunogen | Purified recombinant fragment of human P2RY1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787438 |
Product Specific Information
Amino acid sequence of the immunogen is proprietary. This antibody has been tested in indirect ELISA.
Target Information
P2Y1 is a purinergic receptor that induces platelet shape change and aggregation by binding ADP, leading to mobilization of intracellular calcium via activation of phospholipase C. It also mediates nitric oxide release and may modulate neuronal signal transmission. P2Y1 is expressed in various tissues, particularly in the brain, and ESTs have been isolated from human embryo, lung, and placenta libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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