Thermo Fisher Scientific HBEGF Recombinant Rabbit Monoclonal Antibody (ARC0663)
HBEGF 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체입니다. Western blot 및 ELISA에 적합하며, 높은 특이성과 감도를 제공합니다. HEK293 세포에서 발현되었으며, 액상 형태로 안정적 보관이 가능합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0663 |
| Immunogen | A synthetic peptide corresponding to amino acids 50–150 of human HB-EGF (Q99075) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.52 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849053 |
Product Specific Information
Immunogen sequence:
LLPLGGGRDR KVRDLQEADL DLLRVTLSSK PQALATPNKE EHGKRKKKGK GLGKKRDPCL RKYKDFCIHG ECKYVKELRA PSCICHPGYH GERCHGLSLP V
Target Information
HBEGF is a growth factor that mediates its effects via EGFR, ERBB2, and ERBB4. It is required for normal cardiac valve formation and heart function. HBEGF promotes smooth muscle cell proliferation and may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts but not endothelial cells. It binds EGFR with higher affinity than EGF and is a more potent mitogen for smooth muscle cells. It also acts as a diphtheria toxin receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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