Thermo Fisher Scientific GLUT4 Monoclonal Antibody (1F8)
GLUT4 단백질을 검출하기 위한 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 1F8). Western blot, IHC, ICC 등 다양한 응용에 적합하며, 인간 및 설치류 등 여러 종에 반응. Protein G 정제, 1 mg/mL 농도, PBS buffer에 보관.
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Thermo Fisher Scientific GLUT4 Monoclonal Antibody (1F8)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Pig, Rabbit, Rat |
| Published Species | Human, Rabbit |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F8 |
| Immunogen | Partially purified vesicles containing insulin-responsive glucose transporter 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2191429 |
Product Specific Information
- This antibody does not react with dog.
- Enzyme-mediated antigen retrieval is required prior to staining of paraffin sections (Proteinase K recommended).
- Mouse anti-glucose transporter 4 antibody, clone 1F8, was originally raised against rat intracellular low-density microsomes (James et al.).
Target Information
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter.
In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane.
Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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