Thermo Fisher Scientific E. coli J5 LPS Monoclonal Antibody (2D7/1)

Applications

Western Blot (WB)

• Tested Dilution: Assay-dependent

ELISA

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

This antibody cross-reacts with K. pneumoniae, S. sonnei, and S. typhimurium.
Mouse anti-Escherichia coli J5 LPS antibody, clone 2D7/1 recognizes E. coli J5 LPS.
The J5 mutant of E. coli lacks the enzyme uridine diphosphate glucose 4-epimerase and therefore produces an incomplete LPS, deficient in galactose and all the sugars distal to the central polymers.

Target Information

Escherichia coli (E. coli) are Gram-negative enteric bacteria that live in the human gut.
Its presence in nature is an indication of human fecal pollution.
E. coli also causes human diseases such as urinary tract infections and neonatal meningitis.
Infection with particular enterotoxigenic strains can lead to life-threatening intestinal diseases.
E. coli are distinguished immunologically by serotyping based on three types of antigen:

• Somatic or O antigen (terminal sugars on the cell surface lipopolysaccharide)
• Capsular or K antigens
• Flagellar or H antigens

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.