Thermo Fisher Scientific Interleukin-2 (IL-2) Monoclonal Antibody (IL2/4985)
인간 IL-2 단백질을 인식하는 Mouse IgG2 단클론 항체로, IHC(P) 및 Peptide Array에 사용 가능. 200 µg/mL 농도의 액상 제품이며 Protein A/G로 정제됨. 면역조절 연구 및 T세포 활성화 관련 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IL2/4985 |
| Immunogen | Recombinant fragment (around aa1–153) of human IL2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Human endometrium or tonsil tissue
- Cellular Location: Secreted
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine essential for the proliferation of activated T cells, and differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric complex whose gamma chain is shared by IL-4 and IL-7.
Expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mechanism.
Disruption of an IL-2-like gene in mice causes ulcerative colitis-like disease, indicating IL-2’s critical role in immune response regulation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일: 3558-MSM5-P0_IL-2_P60568-1_House_mouse.svg, 3558-MSM5-P0_IL-2_P60568-1_House_mouse_PDP.jpeg)
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