Thermo Fisher Scientific GCN2 Recombinant Rabbit Monoclonal Antibody (6E2X0)
Recombinant rabbit monoclonal antibody targeting human GCN2 (EIF2AK4). Validated for Western blot and ELISA applications. High purity via Protein A purification, supplied in liquid form with glycerol for stability. Ideal for metabolic stress and amino ...
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Thermo Fisher Scientific GCN2 Recombinant Rabbit Monoclonal Antibody (6E2X0)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6E2X0 |
| Immunogen | Recombinant protein of human GCN2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Target Information
EIF2AK4 (GCN2) is a metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor-2 in response to low amino acid availability. It acts as an activator of the integrated stress response required for adaptation to amino acid starvation. Mutations in this gene are associated with pulmonary veno-occlusive disease 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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