Thermo Fisher Scientific PLSCR1 Polyclonal Antibody
PLSCR1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C에서 보관 가능합니다.
- 카탈로그번호
- PA577045
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human PLSCR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2720772 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as verified by SDS-PAGE.
Target Information
Phospholipid scramblase 1 (PLSCR1) is a calcium-dependent plasma membrane protein involved in the transbilayer movement of phosphatidylserine and other phospholipids upon calcium influx. This process contributes to membrane remodeling and phosphatidylserine exposure in apoptotic cells. PLSCR1 expression is induced by interferons and cytokines, suggesting a role in cytokine signaling pathways. EGF stimulation leads to tyrosine phosphorylation of PLSCR1 (Tyr69, Tyr74), enabling interaction with Shc and linking Src kinase activation to EGF receptor signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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