Thermo Fisher Scientific DDX60L Polyclonal Antibody
Human DDX60L 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 버퍼에 보관. 항바이러스 면역 및 RNA 대사 연구용으로 적합.
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- PA565953
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Thermo Fisher Scientific DDX60L Polyclonal Antibody
Applications and Tested Dilution
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human DDX60L (Recombinant protein control fragment, Product #RP-106642) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663511 |
Product Specific Information
Immunogen sequence:
YAYTMESTDRN QTFSKENETV IQSAYKSLIQ HLEEIRVLVL ATHFEHLKWN DMMEEAYQTL FLLQHLWSEG SDIQR
Highest antigen sequence identity to the following orthologs:
- Mouse: 51%
- Rat: 49%
Target Information
This gene encodes a member of the DExD/H-box helicase family of proteins, a subset of the superfamily 2 helicases. Members of this family share conserved RecA-like domains with motifs for ATP binding, hydrolysis, nucleic acid binding, and RNA unwinding.
These proteins are involved in RNA metabolism and antiviral immunity, acting as cytosolic sensors of viral nucleic acids. The DDX60L protein inhibits hepatitis C virus replication in response to interferon stimulation in cell culture.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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