Thermo Fisher Scientific MTOR Monoclonal Antibody (OTI10A2), TrueMAB
Human mTOR 단백질(aa 1766–2144)에 특이적인 Mouse IgG2a 단클론 항체로, Western blot에 적합. Lyophilized 형태로 제공되며, PBS와 trehalose buffer에 보존. 세포 성장 및 암 연구에 활용 가능.
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Thermo Fisher Scientific MTOR Monoclonal Antibody (OTI10A2), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Publications: - [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1766–2144 of human MTOR produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to reach ~1 mg/mL antibody concentration.
- For conjugation experiments, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
FRAP1 (mTOR) is a serine/threonine kinase essential for cellular growth and proliferation.
Disruption of the mTOR/PI3K/AKT pathway is linked to various cancers.
FRAP1 is the target of rapamycin and its analogs, used as immunosuppressants and cancer therapeutics.
Mutations in this gene are associated with Smith-Kingsmore syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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