Thermo Fisher Scientific IP6K2 Polyclonal Antibody
Thermo Fisher Scientific의 IP6K2 Polyclonal Antibody는 인간 및 마우스 시료에 반응하는 Rabbit IgG 항체입니다. Western blot에 최적화되어 있으며, KLH 결합 합성 펩타이드(aa 226-258)를 면역원으로 사용했습니다. 단백질 A 및 항원 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 226–258 amino acids from the central region of human IP6K2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2634930 |
Target Information
Members of the inositol hexakisphosphate kinase (IP6K) family, including IP6K1 and IP6K2, have high affinity and selectivity for inositol hexakisphosphate (InsP6) as a substrate. These kinases convert InsP6 to PP-InsP5 but show no catalytic activity with other inositol pyrophosphates. InsP6, which inhibits serine/threonine protein phosphatases, increases calcium influx across the plasma membrane and may regulate insulin exocytosis. IP6K1 was purified as a 54 kDa protein in rat brain extracts, while IP6K1 and IP6K2 in mouse were characterized as 50 kDa and 49 kDa proteins, respectively. IP6K1 also exhibits ATP synthase activity, suggesting a role as a high-energy phosphate donor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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