ELK Biotechnology KAT6B rabbit pAb
KAT6B rabbit pAb는 인간 및 마우스에서 반응하는 다클론 항체로, 핵 내 히스톤 아세틸전이효소 KAT6B 단백질 검출에 사용됩니다. WB와 ELISA에 적합하며, 높은 특이성과 안정적인 결합력을 제공합니다. -20°C에서 1년간 보관 가능합니다.
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KAT6B rabbit pAb
Supplier: ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | KAT6B rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 1170–1250) |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 228 kD |
| Gene ID (Human) | 23522 |
| Human Swiss-Prot No | Q8WYB5 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Mouse |
Background
The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and may be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. (RefSeq, Mar 2012)
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