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ELK Biotechnology HASP rabbit pAb
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ELK Biotechnology HASP rabbit pAb

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HASP 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 인간, 랫드, 마우스 시료에 반응하며, 세포 분열 중 염색체 및 방추체 관련 연구에 유용합니다. -20°C에서 1년간 보관 가능합니다.

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pk
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ELK Biotechnology ES9078-100UL HASP rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES9078-50UL HASP rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology HASP rabbit pAb

ELK Biotechnology HASP rabbit pAb

제품 정보

항목 내용
Product name HASP rabbit pAb
Applications WB; ELISA
Recommended Dilutions WB: 1:500–1:2000 / ELISA: 1:5000–1:20000
Immunogen Synthesized peptide derived from human protein (AA range: 270–350)
Host Rabbit
Storage -20°C, 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 87 kDa
Gene ID (Human) 83903
Human Swiss-Prot No. Q8TF76
Cellular Localization Nucleus, Chromosome, Cytoplasm, cytoskeleton, spindle. Nuclear during interphase and associates with chromosomes and spindle apparatus during mitosis.
Species Reactivity Human, Rat, Mouse

Background

  • Catalytic activity: ATP + a protein → ADP + a phosphoprotein
  • Cofactor: Magnesium
  • Function: Required for normal alignment of chromosomes at metaphase. Phosphorylates histone H3 at Thr-3 during mitosis.
  • PTM: Autophosphorylated on serine and threonine residues (By similarity). Phosphorylated during mitosis and upon DNA damage, probably by ATM or ATR.
  • Similarity: Belongs to the protein kinase superfamily, Ser/Thr protein kinase family, Haspin subfamily. Contains one protein kinase domain.
  • Tissue specificity: Strongly expressed in testis. Also present in thymus and bone marrow, with low levels in prostate, intestine, lung, spleen, and lymph node. Expressed in fetal skin, liver, kidney, and small intestine, and in proliferating but not non-proliferating cell lines.

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