ELK Biotechnology RT11 rabbit pAb
RT11 rabbit pAb는 인간, 쥐, 생쥐 시료에 반응하는 폴리클로날 항체로 WB와 ELISA에 적합합니다. 미토콘드리아 단백질 합성 연구에 활용되며, 고순도의 IgG 형태로 제공됩니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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ELK Biotechnology RT11 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | RT11 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 10–90) |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 21 kD |
| GeneID (Human) | 64963 |
| Human Swiss-Prot No | P82912 |
| Cellular Localization | Mitochondrion |
| Species Reactivity | Human; Rat; Mouse |
| Storage | -20°C, 1 year |
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are essential for protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with an estimated 75% protein to rRNA ratio, contrasting with prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins comprising the mitoribosome vary significantly in sequence and biochemical properties among species, hindering recognition by sequence homology. This gene encodes a 28S subunit protein highly similar to ribosomal protein S11P family members. A pseudogene corresponding to this gene is located on chromosome 20, and multiple transcript variants encoding different isoforms have been identified.
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