ELK Biotechnology ARI1A rabbit pAb

제품명

ARI1A rabbit pAb

공급업체

ELK Biotechnology

제품 개요

ARI1A rabbit pAb는 인간 및 마우스에서 반응하는 다클론 항체로, SWI/SNF 복합체 구성 단백질을 표적합니다. 이 단백질은 염색질 구조를 조절하여 유전자 전사를 활성화하는 데 관여합니다.

제품 스펙

Background

This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function: a DNA-binding domain that specifically binds AT-rich sequences recognized by the SNF/SWI complex at the beta-globin locus, and a C-terminal domain that stimulates glucocorticoid receptor-dependent transcriptional activation. The protein may confer specificity to the SNF/SWI complex and recruit it to its targets.