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ELK Biotechnology PDE3A rabbit pAb
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ELK Biotechnology PDE3A rabbit pAb

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PDE3A 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 사용 가능. 세포 내 cAMP와 cGMP 신호 조절 연구에 적합하며, 심혈관 기능 및 혈소판 응집 관련 연구에 활용 가능. -20°C에서 1년 보관.

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pk
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ELK Biotechnology ES9007-100UL PDE3A rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES9007-50UL PDE3A rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology PDE3A rabbit pAb

PDE3A rabbit pAb

제품 정보

항목 내용
Product name PDE3A rabbit pAb
Applications WB; ELISA
Recommended Dilutions WB 1:500–2000, ELISA 1:5000–20000
Immunogen Synthesized peptide derived from human protein (AA range: 250–330)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 125 kD
Gene ID (Human) 5139
Human Swiss-Prot No. Q14432
Cellular Localization Membrane; Multi-pass membrane protein; Cytoplasm, cytosol
Species Reactivity Human; Mouse; Rat

Background

This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
[provided by RefSeq, Sep 2011]

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