ELK Biotechnology CDH3 rabbit pAb
CDH3 단백질을 인식하는 토끼 폴리클로날 항체로, WB와 ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. 세포막 단일 통과형 단백질 검출에 적합. 고순도 IgG, 1 mg/ml 농도, -20°C에서 1년 보관.
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ELK Biotechnology CDH3 rabbit pAb
제품 개요
CDH3 rabbit pAb는 인간 CDH3 단백질을 인식하는 토끼 폴리클로날 항체로, 세포막에 위치한 칼슘 의존성 세포-세포 접착 단백질 검출에 적합합니다. WB 및 ELISA 분석에 사용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CDH3 rabbit pAb |
| Alternative Names | Cadherin-3 (Placental cadherin), P-cadherin |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:10000–20000 |
| Immunogen | Synthesized peptide derived from human CDH3 |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 120 kD |
| GeneID (Human) | 1001 |
| Human Swiss-Prot No | P22223 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail.
This gene is located in a gene cluster on chromosome 16, associated with loss of heterozygosity events in breast and prostate cancer. Aberrant expression is also observed in cervical adenocarcinomas. Mutations are linked to hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).
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