ELK Biotechnology CDH17 rabbit pAb
CDH17 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합. 인간, 마우스, 랫트 시료에 반응하며 세포막 단백질 검출에 활용 가능. 고순도 IgG 형식으로 -20°C에서 1년 보관 가능.
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ELK Biotechnology CDH17 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CDH17 rabbit pAb |
| Alternative Names | Cadherin-17 (Intestinal peptide-associated transporter HPT-1), Liver-intestine cadherin (LI-cadherin) |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:10000–20000 |
| Immunogen | Synthesized peptide derived from human CDH17 Polyclonal |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 99 kDa |
| GeneID (Human) | 1015 |
| Human Swiss-Prot No | Q12864 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene is a member of the cadherin superfamily, encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region with 7 cadherin domains and a transmembrane region but lacking the conserved cytoplasmic domain. It is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step of oral absorption of many peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. (RefSeq, Jan 2009)
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